PureEvo Jacomex VS cell culture isolator Comecer

PureEvo  Jacomex is a high-performance, fully customizable glove box designed to meet the most demanding requirements in scientific and industrial environments. With outstanding modularity, flexibility, and atmospheric control, it is the ideal solution for complex, sensitive processes.

The Cell Culture Isolator by Comecer is a cutting-edge containment system specifically designed for regenerative medicine and tissue engineering applications. It provides a sterile and controlled Class A (ISO 5) environment for handling cells and tissues, ensuring maximum protection against cross-contamination. This system effectively replaces traditional cleanrooms by creating a rigid physical barrier between the operator and biological processes, which is essential for the production of Advanced Therapy Medicinal Products (ATMPs).

• Advanced material research under inert atmosphere
• Preparation, development, and characterization of materials
• Pilot-scale or development-phase processes
• Integration of automated or specialized equipment
• Use in nuclear, ATEX, and pharmaceutical environments
• Controlled-atmosphere industrial processes
• Protection of operators, products, and environment

A tailor-made solution for complex applications

PureEvo  Jacomex is designed for professionals who require maximum reliability, performance, and customization. Its modular construction, advanced interface, and comprehensive options make it the reference solution for achieving high-purity, controlled environments in both research and production.

This isolator is primarily used in the following fields:

• Regenerative Medicine: Expansion and manipulation of stem cells intended for human cell therapies.
• Tissue Engineering: Development of complex biological tissues within a sterile environment.
• ATMP Production: Manufacturing of advanced therapy medicinal products under strict GMP compliance.
• Sensitive Cell Culture: Clinical research requiring absolute protection against atmospheric and human contaminants.

• Autonomous closed-loop purification system – Core 12 and higher
• Maintains O₂ and H₂O levels below 1 ppm
• Operation under positive or negative pressure
• Working gas: nitrogen or argon
• Available in 6 standard sizes – unlimited expansion options
• Single-sided, double-sided, or custom configurations
• Single or dual-line purification units with automatic regeneration
• Two-stage 21 m³/h vacuum pump
• Automatic cycle transfer airlock
• 10-inch high-definition touchscreen
• User-friendly HMI with continuous monitoring of H₂O, O₂, pressure, and temperature
• PLC interface with integrated assistance and maintenance features
• Configurable system status indicator
• Energy Saving mode active 24/7, even during operation
• Optional rounded corners for easier cleaning and decontamination

The isolator features a modular design to adapt to the specific needs of each laboratory. It is constructed from AISI 316L stainless steel with rounded corners to facilitate cleaning. The system maintains unidirectional laminar flow across the entire work area, ensuring constant air purity. A key feature of this equipment is its integrated Vaporized Hydrogen Peroxide (VPHP) decontamination system, allowing for fast and automated sterilization of internal surfaces.

Operation is managed through an intuitive touch screen for real-time monitoring of pressure, humidity, temperature, and gas concentrations ($CO_2$, $O_2$). The isolator can integrate various equipment such as incubators, centrifuges, or microscopes while maintaining the integrity of the containment barrier. Rapid Transfer Ports (RTP) and decontamination airlocks allow for the introduction or removal of sterile materials without compromising the internal Class A environment.