PharmaPure® Tube Sealer - MGA Technologies

PharmaPure® Tube Sealer – MGA Technologies

The PharmaPure® Tube Sealer – MGA Technologies is equipment designed for the sterile disconnection of PharmaPure® tubing used in pharmaceutical, biotechnology and laboratory environments. Developed for aseptic closed-system processes, it enables safe tubing separation operations while minimizing microbiological contamination risks.

Using a controlled thermofusion process, the equipment ensures reliable tube sealing before cutting in order to preserve process integrity during critical operations.

22 Chem. des Prés Secs, 69380 Civrieux-d'Azergues

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    • Sterile disconnection of PharmaPure® tubing

    • Compatible with TPE and PharmaPure® tubing

    • Thermofusion operating process

    • Ceramic heating system

    • Electromagnetic locking system

    • Integrated vane pump cooling system

    • Designed for cleanroom environments

    • Compatible with several tubing diameters:

        • 1/4″

        • 3/8″

        • 1/2″

        • 3/4″

    • Anodized aluminum clamp sets

    • Electrical supply:

        • 110 V

        • 220/230 V

        • 50/60 Hz

    • No compressed air required

PharmaPure® tubing is widely used in sterile filling, fermentation, production filtration and vaccine manufacturing processes. Although highly resistant, these tubes may require replacement during maintenance operations or production changes.

The PharmaPure® Tube Sealer – MGA Technologies enables this operation to be carried out aseptically in controlled environments.

The equipment operates using heated clamps integrating a ceramic heating system. Once the tubing is positioned inside the clamps, an electromagnet locks the system and automatically starts the thermofusion cycle.

The cycle includes several stages:

    • clamp heating above the tube melting point,

    • thermal holding phase to eliminate contaminants,

    • controlled material cooling,

    • secure clamp opening before tubing cutting.

This process helps maintain closed-system integrity while reducing cross-contamination risks during disconnection operations.

The PharmaPure® Tube Sealer – MGA Technologies can be used for:

    • sterile filling lines,

    • biopharmaceutical processes,

    • fermentation operations,

    • production filtration systems,

    • vaccine manufacturing,

    • single-use processes,

    • pharmaceutical laboratories,

    • biotechnology environments,

    • sensitive fluid transfer operations

More Information about the Product or Applications

A solution designed for aseptic pharmaceutical processes

In pharmaceutical and biotechnology industries, fluid transfer operations require equipment capable of maintaining a high level of microbiological safety. Tubing systems used in aseptic processes must be replaceable or disconnected without compromising process integrity.

The PharmaPure® Tube Sealer - MGA Technologies addresses this challenge through a thermofusion process designed to safely seal the tubing before separation.

This technology helps reduce cross-contamination risks during maintenance operations or transfer line replacement.

Equipment designed for closed systems

Modern pharmaceutical manufacturing processes increasingly rely on closed systems to reduce external contamination and secure critical operations.

The PharmaPure® Tube Sealer - MGA Technologies fully supports this approach thanks to its automated operation and compatibility with tubing used in single-use processes.

PharmaPure® tubing also offers excellent mechanical resistance, low permeability and very low particle generation, making it particularly suitable for sensitive biopharmaceutical environments.

A design suitable for cleanroom environments

The PharmaPure® Tube Sealer - MGA Technologies is designed for use in cleanrooms and regulated environments requiring reliable and repeatable equipment.

The system does not require compressed air, making integration easier in controlled production areas. Its automated operation also helps reduce operator handling while improving process safety.

Thanks to its anodized aluminum clamp sets, the equipment can accommodate different tubing diameters to meet the specific needs of pharmaceutical and biotechnology production lines.

MGA Technologies, specialist in aseptic pharmaceutical equipment

With the PharmaPure® Tube Sealer - MGA Technologies, we provide a reliable solution for the sterile disconnection of tubing used in pharmaceutical and biotechnology processes.

Designed for aseptic environments and closed systems, this equipment helps secure critical operations while maintaining the microbiological integrity of industrial processes.

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PharmaPure® Tube Sealer - MGA Technologies

PharmaPure® Tube Sealer – MGA Technologies

The PharmaPure® Tube Sealer – MGA Technologies is equipment designed for the sterile disconnection of PharmaPure® tubing used in pharmaceutical, biotechnology and laboratory environments. Developed for aseptic closed-system processes, it enables safe tubing separation operations while minimizing microbiological contamination risks.

Using a controlled thermofusion process, the equipment ensures reliable tube sealing before cutting in order to preserve process integrity during critical operations.

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