G(Iso) Jacomex VS Downstream Isolator for Cell & Gene Therapy Comecer

The G(Iso) glove box by Jacomex is built from welded stainless steel to deliver outstanding strength, airtightness, and versatility. Designed to protect the operator, the product, or both, it adapts to the most demanding environments thanks to a wide range of technical options that meet even the strictest protocols.

The Downstream Isolator for Cell & Gene Therapy process by Comecer is an isolator dedicated to the final part of a cell therapy or biological process. Its primary role is to allow users to collect products from the expansion or maturation process and eventually prepare them for delivery to the end customer. This equipment ensures the maintenance of product sterility and integrity during critical packaging stages.

Scientific research

Under inert or dry atmosphere, the G(Iso) safeguards air- and moisture-sensitive samples for chemistry, battery work, and materials science.

Nuclear and pharmaceutical industry

Its high leak-tightness securely contains radioactive or toxic substances, protecting both staff and the outside environment.

Custom projects

Thanks to its exceptional modularity, the G(Iso) can integrate vacuum pumps, weighing stations, or dedicated sensors to support complex, tightly controlled workflows.

This isolator is primarily used for:

• ATMP Process Finalization: Final preparation of gene and cell therapies.
• Aseptic Conditioning: Filling infusion bags or vials for long-term storage.
• Cryopreservation Preparation: Secure handling of samples before freezing.
• Logistical Distribution: Final packaging of biological products before shipment to healthcare centers.

• One-piece 304L stainless-steel body (316L optional), 3 mm thick
• Removable side panels with sealing gaskets
• Fully customizable glove-port count and internal volume
• Quick-load transfer chamber or interchangeable side door
• Safety viewing window in tempered glass or polycarbonate
• Compatibility with sensors, analyzers, manipulators, and atmosphere-purification systems
• Available on fixed or mobile stand

The configuration of this isolator is flexible and adapts to the specific nature of the product to be delivered. Depending on requirements, the isolator may include the following areas:

• Collection Area: For recovering cells or biological products after the maturation phase.
• Filling Area: Equipment for filling into vials or bags intended for infusion, cryopreservation, or other administration methods.
• Packaging Area: A dedicated space if the final product requires a specific packaging step under a controlled environment.
• Manufacturing Intelligence: The isolator can be paired with Illuminate™ technology, which provides real-time machine performance data to maximize line throughput, improve product quality, and reduce downtime.